ABOUT THE INTERPLAY OF SENSITIVE AND RESISTANT BIOTYPES IN WEED POPULATIONS - SIMULATION EXERCISES FOR ECHINOCHLOA CRUS-GALLI IN MAIZE CROPS

About the interplay of sensitive and resistant biotypes in weed populations - simulation exercises for Echinochloa crus-galli in maize crops

Weed species easily establish in crops with a similar life cycle.Especially mono-cropping provides best conditions for such weeds.In maize this is true for Echinochloa crus-galli, TOTAL REPAIR SHAMPOO which is a C4 plant and one of the worst weeds worldwide.In Germany E.crus-galli is one of the few typical weed species in maize.When recurrent herbi

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Discovering covalent cyclic peptide inhibitors of peptidyl arginine deiminase 4 (PADI4) using mRNA-display with a genetically encoded electrophilic warhead

Abstract Covalent drugs can achieve high potency with long dosing intervals.However, concerns remain about side-effects associated with off-target reactivity.Combining macrocyclic peptides with covalent warheads provides a solution to minimise off-target reactivity: the peptide enables highly specific target binding, positioning a weakly reactive w

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